Dr. Antony Browne, AKA Antony Brown, Tony Browne,
Department of Computing,
School of Engineering and Physical
Sciences,
University of Surrey,
Guildford, SURREY,
GU2 7XH, UK
a<dot>browne<at>surrey.ac.uk
Taught
Courses:
- CS263 Information Modelling Here:
- CSM10 Intelligent Information Systems Here:
- CS365 Neural Networks Here:
Research Interests:
- Computational models of psychiatric illness
- Adaptive autonomous robotics
- Connectionist modelling of variable binding,
inference and extrapolation.
- Neural networks for novelty detection,
forecasting and prediction.
- Structure and rule extraction from trained
neural networks, including a current BBSRC/EPSRC supported joint project
with Centre for Molecular Design at Portsmouth University.
This project involves understanding relationships in biological data by
rule extraction from neural networks. Details Here:
Downloadable Technical
Reports and Preprints:
Browne, A., Jakary, A. Vinogradov,
S., Fu, Y. and R. F. Deicken Automatic Relevance Determination for Identifying
Thalamic Regions Implicated in Schizophrenia. To appear in IEEE Transactions on Neural Networks Preprint here (pdf):
Abstract. There have been many theories about and computational
models of the schizophrenic disease state. Brain imaging techniques have
suggested that abnormalities of the thalamus may contribute to the pathophysiology of schizophrenia. Several studies have
found the thalamus to be altered in schizophrenia, and the thalamus has
connections with other brain structures implicated in thedisorder.
This paper describes an experiment examining thalamic levels of the metabolite
N-acetylaspartate (NAA), taken from schizophrenics and controls using in-vivo
proton magnetic resonance spectroscopic imaging. Automatic relevance
determination was performed on neural networks trained on this data,
identifying NAA group differences in the pulvinar and mediodorsal nucleus,
underscoring the importance of examining thalamic subregions in schizophrenia.
Browne, A., Hudson, B. D.,
Whitley, D. C., Ford, M. G. & Picton, P. (2004) Biological data mining with
neural networks: Implementation and application of a flexible decision tree
extraction algorithm to genomic problem domains. Neurocomputing, 57,
275-293. Elsevier - ISSN: 0925-2312. Preprint here (pdf):
Browne, A. (2002).
Representation and extrapolation in multi-layer perceptrons.
Neural Computation, 14(7), 1739-1754. ISSN: 0899-7667. Preprint
here (pdf):
Browne, A. & R. Sun.
(2001). Connectionist inference models. Neural Networks, 14(10), 1331-1355.
ISSN: 0893-6080. Preprint
here (pdf):
Selected Publications:
Textbooks:
- Browne, A. (Ed.) (1997). Neural Network
Perspectives on Cognition and Adaptive Robotics. Institute
of Physics Press, Bristol, UK. ISBN 0-7503-0455-3.
- Browne, A. (Ed.) (1997). Neural Network
Analysis, Architectures and Algorithms. Institute
of Physics Press, Bristol, UK. ISBN 0-7503-0499-5.
Journal Papers:
- Hudson, B, Whitley, D., Browne, A.,
and Ford, M. (2005) Extraction of comprehensible logical rules from neural
networks: Applications in Bio and Cheminformatics,
Croatica Chemica Acta, 78, 557-561 ISSN: 0011-1643.
- Bose, S., Kazemian,
H., White, K. & Browne., A. (In Press) Use Of Neural Networks To
Predict And Analyse Membrane Proteins In The Proteome. BMC Bioinformatics.
ISSN 1471-2105.
- Yang, S. and Browne, A. (2004) Neural Network
Ensembles: Combining Multiple Models for Enhanced Performance Using a
Multistage Approach. Expert Systems, 21(5), 279-288. Blackwells - ISSN: 0266-4720.
- Browne, A., Hudson, B. D., Whitley, D. C. ,
Ford, M. G. and Picton, P. (2004) Biological data mining with neural
networks: Implementation and application of a flexible decision tree
extraction algorithm to genomic problem domains. Neurocomputing,
57, 275-293. Elsevier - ISSN: 0925-2312.
- Browne, A. (2002). Representation and
extrapolation in multi-layer perceptrons. Neural
Computation, 14(7), 1739-1754. MIT Press - ISSN: 0899-7667.
- Browne, A. & R. Sun. (2001). Connectionist
inference models. Neural Networks, 14(10), 1331-1355. Elsevier -
ISSN: 0893-6080.
- Browne, A. & R. Sun (1999). Connectionist variable
binding. Expert Systems, 16(3), 189-207. Blackwells
- ISSN: 0266-4720.
- Browne, A. & P. Picton (1999). Two analysis
techniques for feed-forward networks. Behaviormetrika:
Special Issue on Analysis of Knowledge Representations in Neural Network
Models 26(1), 75-87. ISSN: 0385-7417.
- Browne, A. (1998). Detecting systematic
structure in distributed representations. Neural Networks 11(5),
815-824. Elsevier - ISSN: 0893-6080.
- Browne, A. (1998). Performing a symbolic
inference step on distributed representations. Neurocomputing 19,
23-34. Elsevier - ISSN: 0925-2312.
- Browne, A. (1996). Measuring distribution in
distributed representations. Neural Processing Letters, 3, 73-79.
ISSN: 1370-4612.
- Browne, A. & J. Pilkington (1994). Unification
using a distributed representation. Association for Computing Machinery
bulletin on Artificial Intelligence, 5(2), 5-7.
Conference
Papers:
- Bose, S., Kazemian ,H.
,White ,K & Browne., A. (2005) Use Of Neural Networks To Predict And
Analyse Membrane Proteins In The Proteome. Proceedings of the
Bioinformatics and Systems Biology Conference, Edinburgh, UK,
18.
- Browne, A., Hudson, B., Whitley, D. & Ford,
M. (2004) Neural networks for knowledge discovery from bioinformatic
and cheminformatic datasets. Proceedings of the
Fifth International Conference on Recent Advances in Soft Computing,
Nottingham UK,
pp. 74-79. ISBN 1-84233-110-8.
- Bose ,S., Browne, A., Kazemian,
H. & White, K. (2004) Applying Perl to data set creation for
biological data mining. Poster at 12th International Conference on
Intelligent Systems for Molecular Biology (ISMB) and 3rd European
Conference on Computational Biology, Glasgow,
UK.
- Bose ,S., Browne, A., Kazemian,
H. & White, K. (2004). Predicting membrane spanning regions with
neural networks. Poster at Young Bioinformaticians'
Forum at Royal Society of Chemistry Molecular Modeling
Group, Oxford, UK. (ii)
- Bose ,S., Browne, A., Kazemian,
H. & White, K. (2004). Neural networks for membrane protein detection.
Royal Society of Chemistry Symposium on Chemical Technologies in
Pharmaceutical Industry, London,
UK.
- Bose, S., Browne, A., Kazemian,
H. and White, K. (2003) Knowledge Discovery in Bioinformatics using Neural
Networks. Proceedings Sixth International Conference on Computer and
Information Technology (ICCIT), Dhaka,
Bangladesh,
707-712. ISBN: 984-584-005-1.
- Hudson, B. D., Whitley, D. C., Browne, A. and Ford, M. G. (2003)
Rule Induction from Neural Networks. Application of TREPAN in Bio and Chemoinformatics Proceedings 18th International
Conference on Mathematics and Computing in Chemistry, Dubrovnik, 23-29th June 2003. ISBN:
953-6690-27-6
- Browne, A., Hudson, B., Whitley, D. and Picton, P. (2003)
Knowledge extraction from neural networks. Proceedings of the 29 th Annual Conference of the IEEE Industrial
Electronics Society, Roanoke, Virginia, USA, 1909-1913.
- Browne, A., Hudson, B., & Whitley, D. (2002) Understanding
splice junctions via knowledge extraction from a neural network. BBSRC
Bioinformatics Workshop, Warwick,
UK.
- Yang, S. & Browne, A. (2002). Multistage neural networks:
Adaptive combination of ensemble results. Proceedings of the Fourth
International Conference on Recent Advances in Soft Computing (RASC2002),
Nottingham, UK , pp. 55-60, ISBN:
1-84233-0764.
- Hudson, B., Whitley, D., & Browne, A. (2002) Biological data
mining: high fidelity rule extraction from trained neural networks. Proceedings
of the Fourteenth European Symposium on Quantitative Structure-Activity
Relationships, Bournemouth,
UK.
Blackwell Scientific, in press.
- Browne, A. (2002). Modeling the
extrapolation ability of multi-layer perceptrons.
Proceedings of the Sixth World Conference on Systemics,
Cybernetics and Informatics (SCI 2002), Orlando,
FL, 429-433, ISBN: 980-07-8150-1 .
- Yang, S. & Browne, A. (2002). Multistage Neural Network
Ensembles. Proceedings of the Third International Workshop on Multiple
Classifier Systems, Caligari,
Italy, published as
Lecture Notes in Computer Science 2364, Springer Verlag, Berlin,
Heidelberg,
2002. ISBN: 3-540-43818-1.
- D. Whitley, A. Browne, A. Azad & M. Ford (2001). Enhancing
rule extraction from neural networks. BBSRC Bioinformatics Workshop,
Hinxton, February.
- A. Browne & H. B. Kazemian (2000).
Data mining with neural networks. Proceedings of the Fourth
World Multiconference on Systemics, Cybernetics and Informatics;
- The Sixth International Conference on Information Systems,
Analysis and Synthesis, SCI'2000 and ISAS'2000, Orlando, USA,
626-629.
- M. Ford, A. Browne, D. Whitley & S. Chang
(2000). Rule extraction from neural networks trained to model biological
data. BBSRC Bioinformatics Workshop, Hinxton,
February.
S. A. Amin, D. Evans & A. Browne (1999). An
Environment for Developing Low Level Image Processing on Parallel
Computers. Proceedings of the 17th IASTED International Conference on
Applied Informatics.
- Ampratwum, C. S., P. D. Picton, A. A. Hopgood & A. Browne (1998). Hybridisation
Techniques in Optical Emission Spectral Analysis. Proceedings of the
11th International Conference on Industrial and Engineering Applications
of Artificial Intelligence and Expert Systems, pp. 347-356.
- Ampratwum C. S., P. D. Picton & A.
Browne (1998). Rule Extraction from Neural Network Models of Chemical
Species in Optical Emission Spectra. Proceedings of the Workshop on
Recent Advances in Soft Computing, pp. 53-6.
- Browne, A., R. Pascalis
& S. Amin (1996). Signal and Image
Processing with Neural Networks. Proceedings of Circuits, Systems and
Computers 96, Vol. 1, pp. 335-339.
- Browne, A. & J. Pilkington (1994) Variable
Binding in a Neural Network using a Distributed Representation. Proceedings
of the European Symposium on Artificial Neural Networks, Brussels, April
20th-22nd 1994, (pp. 199-204), ISBN 29600049 1 4.
- Browne, A. & J. Pilkington (1994). [Invited
Paper] Performing Variable Binding with a Neural Network. Proceedings
of the Seminar on Adaptive Computing and Information Processing, Brunel University, 25-27 January 1994 (pp.
758-770).
- Browne, A. & J. Pilkington (1994). Variable
Binding using a Distributed Representation: A case study of Unification. Proceedings
of the IEE Colloquium on Symbolic and Neural Cognitive Engineering,
14th February 1994 (pp. 4.1-4.4).
- Browne, A. & J. Pilkington (1994)
Quantifying the amount of distribution present in a Distributed
Representation. Proceedings of the Symposium on Artificial Intelligence
and Neural Networks, Ankara
, June 22nd -24th 1994 (pp. 321-326) ISBN 975 7679 07 0.
- Browne, A. & J. Pilkington (1994) Performing
Structure-Sensitive Processes on Distributed Representations.
Proceedings of INNC 94, Dublin
, Sept. 12th-13th 1994 (pp. 19-24).
Textbook Chapters:
- Yang, S. Browne, A. & Picton, P. (2004)
Multistage Neural Networks: Adaptive Combination of Ensemble Results. In
by A. Lotfi (Editor), & J. Garibaldi (Eds.)
Applications and Science in Soft Computing, Springer Verlag , Berlin. ISBN:
3540408568
- Hudson, B., Whitley, D. & Browne, A (2003).
Biological data mining: High fidelity rule extraction from trained neural
networks. In M. Ford, D,. Livingstone, J. Dearden
& H. Van de Waterbeemd (Eds.) Designing
Drugs and Crop Protectants: Processes, Problems
and Solutions. Blackwell Publishing, Oxford,
UK. pp.
361-363. ISBN: 1-4051-2516-0.
- Browne, A. & J. Pilkington (1995). Variable
binding using a neural network. In Neural Networks by J. Taylor
(Ed.). Alfred Waller Press. ISBN: 1-872474-27-6.
- Browne, A. (1997). Challenges for Neural
Computing. In A. Browne (Ed.) Neural Network Perspectives on Cognition
and Adaptive Robotics. Institute
of Physics Press, Bristol, UK. ISBN 0-7503-0455-3.
Guest Editorials:
- Browne, A. (1999) Symbol processing - a
challenge for neural networks? Expert Systems: The International
Journal of Knowledge Engineering and Neural Networks 16(2), 58-59.
ISSN: 0266-4720.
- Edited a special issue in 2000 of ‘Expert
Systems: The International Journal of Knowledge Engineering and Neural
Networks’, 17 (1) on Performing Symbolic Processing with Neural
Networks. ISSN: 0266-4720.